Institut de Biologie de l'École Normale Supérieure ENS . CNRS UMR8197 . Inserm U1024 Directeur : Pierre Paoletti

Actin-based deformations of the nucleus control mouse multiciliated ependymal cell differentiation.

Marianne Basso, Alexia Mahuzier, Syed Kaabir Ali, [...] Julie Plastino, Nathalie Spassky, Nathalie Delgehyr

Dev Cell. 2024 Dec 10:S1534-5807(24)00673-7. doi:10.1016/j.devcel.2024.11.008

Cécile Charrier, lauréate de l’appel d’offre ERC "Consolidator Grant" 2024

Pour son projet, synMODIFIERS | Human-specific modifiers of synapses in development, plasticity and disorders

Cyclin O controls entry into the cell-cycle variant required for multiciliated cell differentiation

Michella Khoury Damaa, Jacques Serizay, Rémi Balagué, Amélie-Rose Boudjema, Marion Faucourt, Nathalie Delgehyr [...] Nathalie Spassky, Alice Meunier

Cell Rep. 2025 Jan 28 ;44(1):115117. doi : 10.1016/j.celrep.2024.115117.

Cyclin switch tailors a cell cycle variant to orchestrate multiciliogenesis

J Serizay, M Khoury Damaa, A-R Boudjema, R Balagué, M Faucourt, N Delgehyr, C Noûs, L-E Zaragosi, P Barbry, N Spassky, R Koszul, A Meunier

Cell Rep. 2025 Jan 28 ;44(1):115103. doi : 10.1016/j.celrep.2024.115103

Gaskell, Langley, and the "para-sympathetic" idea

Jean-François Brunet

Elife. 2025 Mar 14:14:e104826. doi : 10.7554/eLife.104826

Insulation between adjacent TADs is controlled by the width of their boundaries through distinct mechanisms

Andrea Papale^#, Julie Segueni^#, Hanae El Maroufi, Daan Noordermeer, David Holcman

Proc Natl Acad Sci USA. 2025 Mar 18 ;122(11):e2413112122. doi : 10.1073/pnas.2413112122.

Negative global-scale association between genetic diversity and speciation rates in mammals

Ana C Afonso Silva, Odile Maliet, Leandro Aristide, David Nogués-Bravo, Nathan Upham, Walter Jetz , Hélène Morlon

Nat Commun. 2025 Feb 20 ;16(1):1796. doi : 10.1038/s41467-025-56820-y.

Persistent, Private, and Mobile Genes : A Model for Gene Dynamics in Evolving Pangenomes.

Jasmine Gamblin, Amaury Lambert, François Blanquart.

Mol Biol Evol. 2025 Jan 6 ;42(1):msaf001. doi : 10.1093/molbev/msaf001

RNA anchoring of Upf1 facilitates recruitment of Dcp2 in the NMD decapping complex

Nadia Ruiz-Gutierrez, Jeanne Dupas, Elvire Auquier, Irène Barbarin-Bocahu, Claudine Gaudon-Plesse, Cosmin Saveanu, Marc Graille, Hervé Le Hir

Nucleic Acids Res. 2025 Feb 27 ;53(5):gkaf160. doi : 10.1093/nar/gkaf160

Selection Can Favor a Recombination Landscape That Limits Polygenic Adaptation

Tom Parée, Luke Noble, Denis Roze, Henrique Teotónio.

Mol Biol Evol. 2025 Jan 6 ;42(1):msae273. doi : 10.1093/molbev/msae273.

The public health co-benefits of strategies consistent with net-zero emissions : a systematic review

Léo Moutet, Paquito Bernard, Rosemary Green, James Milner, Andy Haines, Rémy Slama, Laura Temime, Kévin Jean

Lancet Planet Health. 2025 Feb 7:S2542-5196(24)00330-9. doi : 10.1016/S2542-5196(24)00330-9.

Unraveling microglial spatial organization in the developing human brain with DeepCellMap, a deep learning approach coupled with spatial statistics

T. Perochon, Z. Krsnik, M. Massimo [...] T. Lagache, D. A Menassa, D.Holcman

Nat Commun. 2025 Feb 13 ;16(1):1577. doi : 10.1038/s41467-025-56560-z

Vesicular and non-vesicular extracellular small RNAs direct gene silencing in a plant-interacting bacterium

A. Ravet^#, J. Zervudacki^#, M. Singla-Rastogi, M. Charvin, O. Thiebeauld, A. L Perez-Quintero, L. Courgeon, A. Candat, L. Lebeau, A. Emidio Fortunato, V. Mendu, L. Navarro.

Nat Commun. 2025 Apr 14 ;16(1):3533. doi : 10.1038/s41467-025-57908-1.