Institut de Biologie de l'École Normale Supérieure ENS . CNRS UMR8197 . Inserm U1024 Directeur : Pierre Paoletti

Shifted PAMs generate DNA overhangs and enhance SpCas9 post-catalytic complex dissociation

Jinglong Wang, Julien Le Gall, Richard L Frock, Terence R Strick

Nat Struct Mol Biol. 2023 Nov;30(11):1707-1718. doi: 10.1038/s41594-023-01104-6.

Cécile Charrier, lauréate de la "Chaire d’excellence en biologie / santé" de France 2030

Éclaircir les mystères du néocortex pour comprendre les principaux troubles neurologiques.

Chaotic turnover of rare and abundant species in a strongly interacting model community

Emil Mallmin, Arne Traulsen, Silvia De Monte.

Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2312822121. doi: 10.1073/pnas.2312822121.

CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny

N. Assendorp, M. Fossati, B. Libé-Philippot, E. Christopoulou, M. Depp, R. Rapone, F. Dingli, D. Loew, P. Vanderhaeghen, C. Charrier

Cell Rep. 2024 Oct 22;43(10):114797. doi: 10.1016/j.celrep.2024.114797

Exon-junction complex association with stalled ribosomes and slow translation- independent disassembly

Olivier Bensaude, Isabelle Barbosa, Lucia Morillo, Rivka Dikstein, Hervé Le Hir

Nat Commun. 2024 May 17;15(1):4209. doi: 10.1038/s41467-024-48371-5.

Imbalanced speciation pulses sustain the radiation of mammals

Ignacio Quintero, Nicolas Lartillot, Hélène Morlon.

Science. 2024 May 31;384(6699):1007-1012. doi: 10.1126/science.adj2793

Limited ecological opportunity influences the tempo of morphological evolution in birds

Jonathan P Drury, Julien Clavel, Joseph A Tobias, Jonathan Rolland, Catherine Sheard, Hélène Morlon

Curr Biol. 2024 Jan 4:S0960-9822(23)01755-4. doi: 10.1016/j.cub.2023.12.055.

MaxImmun, a new project funded under the European Innovation Council, coordinated by Brice Sperandio, researcher at INSERM | IBENS

Microglia maintain structural integrity during fetal brain morphogenesis

Lawrence AR, Canzi A^*, Bridlance C^* […] Thion MS^#, Lokmane L^#, and Garel S^#

Cell. 2024 Jan 31:S0092-8674(24)00044-8. doi: 10.1016/j.cell.2024.01.012.

Microglial TNFα controls daily changes in synaptic GABA_ARs and sleep slow waves

Maria Joana Pinto, Lucy Bizien, Julie M.J. Fabre, Nina Ðukanović, Valentin Lepetz, Fiona Henderson, Marine Pujol, Romain W. Sala, Thibault Tarpin, Daniela Popa, Antoine Triller, Clément Léna, Véronique Fabre, Alain Bessis

J Cell Biol (2024) 223 (7): e202401041. doi: 10.1083/jcb.202401041

Neural tube-associated boundary caps are a major source of mural cells in the skin

Gerschenfeld G, Coulpier F, Gresset A, Pulh P, Job B, Topilko T, Siegenthaler J, Kastriti ME, Brunet I, Charnay P, Topilko P.

Elife. 2023 Dec 14:12:e69413. doi: 10.7554/eLife.69413

Single-molecule reconstruction of eukaryotic factor-dependent transcription termination

Ying Xiong, Weijing Han, Chunhua Xu, Jing Shi, Lisha Wang, Taoli Jin, Qi Jia, Ying Lu, Shuxin Hu, Shuo-Xing Dou, Wei Lin, Terence R. Strick, Shuang Wang, Ming Li

Nat Commun. 2024 Jun 15;15(1):5113. doi: 10.1038/s41467-024-49527-z

Structural basis of DNA crossover capture by Escherichia coli DNA gyrase 

Marlène Vayssières, Nils Marechal, Long Yun, Brian Lopez Duran, Naveen Kumar Murugasamy, Jonathan M. Fogg, Lynn Zechiedrich, Marc Nadal*, Valérie Lamour* 

Science, 2024, April 12. Vol 384, Issue 6692. doi: 10.1126/science.adl5899

The pelvic organs receive no parasympathetic innervation

Margaux Sivori^#, Bowen Dempsey^#, Zoubida Chettouh, Franck Boismoreau, Maïlys Ayerdi, Annaliese Eymael, Sylvain Baulande, Sonia Lameiras, Fanny Coulpier, Olivier Delattre, Hermann Rohrer, Olivier Mirabeau^#, Jean-François Brunet^#

Elife. 2024 Mar 15:12:RP91576. doi: 10.7554/eLife.91576