ENS - Départment de biologie

Tobias BONHOEFFER How Experience Changes Synapses in the Mammalian Brain

Marie Embs — 2016-06-13T09:00:00Z

One of the most fundamental properties of the brain is its ability to adapt rapidly to environmental changes. This is achieved mainly by changes in the connectivity between individual nerve cells. We have, over the years, investigated many different aspects of the underlying mechanisms, in particular morphological changes that occur alongside with the process of strengthening and weakening of individual synapses. The discovery – obtained in vitro – that such changes occur on the level of dendritic spines has been an important one but it is equally important to investigate whether such changes also occur in the intact brain during synaptic plasticity and learning. We have therefore used new imaging methods to investigate the effects of sensory experience on synaptic changes in cortical circuits. In particular, in vivo two-photon microscopy has enabled us to study morphological as well as functional plasticity at the level of individual neurons in the neocortex of anesthetized and lately also behaving animals. These experiments are now closing the gap between traditional cellular and systems studies, and they will enable us to obtain a much more comprehensive understanding of the phenomenon of synaptic plasticity and its role in cortical function and ultimately behavior.

- 2015 / Séminaire de l'IBENS

Amandine PALUD Liquid-Liquid Phase Separation Mediated by Low Complexity Sequence Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

2015-12-21T14:00:00Z

à 15h
La soutenance de thèse d'Amandine PALUD aura lieu dans la salle Favard, IBENS 46 rue d'Ulm 75005 Paris

- 2015 / Soutenance de thèse

Arp Schnittger Control of entry and progression through meiosis

2015-12-18T10:00:00Z

11h à 12h
Le séminaire de Arp Schnittger (Université Hamburg - Allemagne) aura lieu dans la salle Favard, IBENS 46 rue d'Ulm 75005 Paris

- 2015 / Séminaire de l'IBENS

Charles FFRENCH-CONSTANT Smart wiring - myelin formation and plasticity in the CNS

2015-12-14T10:00:00Z

A traditional view of myelin would be as a passive insulator, formed during development with sheaths of lengths and thicknesses strictly proportionate to axon diameter. It is clear however that this simplistic view is incorrect and that myelin plasticity makes an important contribution to the ability of the CNS to respond to and learn from experience. This highlights the need to under the intrinsic and extrinsic cues that regulate sheath formation and adaption, and these will be the focus of my seminar.

- 2015 / Séminaire de l'IBENS

Ana Eulalio Unraveling hidden roles of microRNAs in bacterial pathogen-host interaction

2015-12-07T10:00:00Z

11h à 12h30

Le séminaire de Ana Eulalio (Würzburg University, Germany) aura lieu dans la salle Favard, IBENS 46 rue d'Ulm 75005 Paris

Climate and Health Conference How climate change impacts public health ? What are the risks for individual and collective health ? How to deal with these climate issues ?

Frédérique Godfroid — 2015-12-06T08:12:00Z

Climate and Health Conference

December 6, Sunday - from 11.30 am to 1.30 pm

followed by a cocktail

Ecole Normale Supérieure
45, rue d'Ulm - 75005 Paris
(RER B Luxembourg)

Organized by the Paris Sciences et Lettres Foundation, the Pasteur Institute and the Mérieux Foundation.

Atmospheric pollution, food security, water supply, propagation of endogenous species, new outbreaks of infectious diseases, all of which are affecting the global health context.
How climate change impacts public health ? What are the risks for individual and collective health ? How to deal with these climate issues ?

Speakers

The impact of climate change on the health of the frontline communities by Runa Kahn, Founder of the NGO Friendship in Bangladesh.
Climate change and Health precariousness by Jeanine Rochefort, responsible of the Seine-Saint-Denis welcome center, Médecins du Monde (MDM)
How response to the vector-borne disease threat ? by Anna-Bella Failloux, Entomologist- Institut Pasteur.
Soon dengue in France ? How to fight ? by Jean Lang, VP Research and Development- Sanofi Pasteur.
National and International Climate and Health Declarations by Nick Watts - The Global Climate and Health Alliance

Roundtable moderate by Benoit Miribel, President of the French Foundation Center and Director of the Merieux Foundation.

Kindly RSVP to : ivan.tudor, centre-francais-fondations.org
Phone : + 33 1 83 79 98 87
Site internet Fondations et Climat

Volker HAUCKE Where the tortoise and the hare meet - clathrin & adaptors in synaptic vesicle cycling

2015-11-30T10:00:00Z

The function of the nervous system depends on the exocytotic release of neurotransmitter from synaptic vesicles (SVs). To sustain neurotransmission SV membranes need to be retrieved and SVs have to be reformed locally within presynaptic nerve terminals. In spite of more than forty years of research the mechanisms underlying presynaptic membrane retrieval and SV recycling remain controversial. In my talk I will present latest data regarding the molecular mechanisms of presynaptic membrane retrieval and SV reformation and the role of endocytic proteins in these processes.

- 2015 / Séminaire de l'IBENS

Vincent CASTRIC Epigenetic control of dominance and recessivity by small non-coding RNAs : resolving a 80 years-long controversy

2015-11-20T10:00:00Z

11h à 12h30
Le séminaire de Vincent CASTRIC (Université de Lille 1) aura lieu dans la salle Favard, IBENS 46 rue d'Ulm 75005 Paris

- 2015 / Séminaire de l'IBENS

Charlie Baer Mutation rates and stress in Caenorhabditis

Marie Embs — 2015-11-12T10:00:00Z

11h à 12h30
Le séminaire de Charlie Baer (University of Florida, Gainsville) aura lieu dans la salle 502, 5e étage, IBENS 46 rue d'Ulm 75005 Paris

- 2015

Christian Schlotterer Evolution of gene expression in Drosophila

Marie Embs — 2015-11-10T10:00:00Z

11h à 12h30
Le séminaire de Christian Schlotterer (VetMed University, Vienna) aura lieu dans la salle 502, 5e étgae, IBENS 46 rue d'Ulm 75005 Paris

- 2015